Trying to conceive without success can be emotionally exhausting. Many women feel confused, anxious or even guilty, yet infertility is a medical condition, not a personal failing. In most cases there is an identifiable factor, and with careful evaluation many couples find a clear way forward.
This page explains the common causes of female infertility, how a fertility specialist investigates them, and the treatment options available. It is general educational information. Every couple's situation is different, and the right plan can only be decided after a personal clinical assessment.
Infertility is generally defined as not achieving pregnancy after 12 months of regular, unprotected intercourse. For women aged 35 and above, evaluation is usually advised after 6 months, and women over 40 or those with known risk factors should not wait that long. Infertility can be primary, when a woman has never conceived, or secondary, when she has conceived before but is now unable to do so.
Fertility depends on both partners. In a significant proportion of couples, a female factor, a male factor or both are involved, and in some couples no cause is found at all. For this reason, a complete evaluation usually includes the male partner as well.
Consider a consultation if any of the following apply:
Conception requires a healthy egg to be released, a clear path for the egg and sperm to meet, a receptive uterus and a balanced hormonal environment. A problem at any of these steps can reduce fertility.
Irregular or absent ovulation is one of the most frequent causes. Polycystic ovary syndrome (PCOS or PCOD) is a leading reason, and thyroid disorders, raised prolactin levels, significant weight changes and excessive stress or exercise can also disturb ovulation. Irregular or missed periods are often the first sign.
If the fallopian tubes are blocked or damaged, the egg and sperm cannot meet. Previous pelvic infection, pelvic inflammatory disease, past abdominal or pelvic surgery, genital tuberculosis or an earlier ectopic pregnancy can all affect the tubes.
In endometriosis, tissue similar to the uterine lining grows outside the uterus. It may cause painful periods, pelvic pain or pain during intercourse, and can affect the ovaries, tubes and egg quality. Some women with endometriosis have few symptoms, so it is sometimes discovered only during a fertility work-up.
Fibroids, polyps, adhesions (scar tissue) or a uterine septum can interfere with implantation or the growth of an early pregnancy. These conditions are usually detected by ultrasound or hysteroscopy.
Egg quantity and quality decline naturally with age, and the decline becomes more pronounced after the mid-30s. Reduced ovarian reserve can also occur earlier because of genetics, ovarian surgery, certain treatments or unknown reasons.
In some couples, standard tests show no clear abnormality. This does not mean there is no solution; treatment can still be offered, guided by age, duration of infertility and previous outcomes.
The aim of the evaluation is to find the cause or causes in an organised, step-by-step way, using only the tests that are relevant to you.
The first visit includes questions about menstrual cycles, previous pregnancies, past infections or surgeries, medical conditions, medicines, lifestyle and how long you have been trying. A general and pelvic examination is performed where appropriate.
Depending on your history, tests may include thyroid function, prolactin, and reproductive hormones such as FSH, LH and estradiol. Anti-Mullerian hormone (AMH) is commonly used, along with ultrasound findings, to estimate ovarian reserve. Ovulation may also be confirmed through cycle tracking or follicular monitoring.
An ultrasound examines the uterus and ovaries, looks for fibroids, polyps, cysts or features suggesting PCOS, and counts the small resting follicles in the ovaries (antral follicle count).
Tubal patency may be checked with hysterosalpingography (HSG), a special X-ray test, or with ultrasound-based techniques. If needed, hysteroscopy allows the inside of the uterus to be viewed directly, and laparoscopy allows the pelvis to be examined and, in many cases, treated in the same procedure.
A semen analysis is a simple, important test and is usually advised at the beginning of the work-up, so that treatment is planned for the couple as a whole.
Treatment is chosen according to the cause, your age, ovarian reserve, how long you have been trying and your preferences. Not every woman needs advanced treatment, and a more complex procedure is not always a better one.
Healthy weight, balanced nutrition, regular activity, stopping tobacco, limiting alcohol and managing stress can support ovulation and overall fertility. Treating thyroid disorders, raised prolactin or other medical conditions is an important first step for many women.
For women with irregular ovulation, such as in PCOS, oral medicines or injectable hormones may be used to stimulate ovulation, with ultrasound monitoring to guide dosing and timing and to reduce risks.
In IUI, prepared sperm is placed in the uterus around the time of ovulation. It may be considered for selected couples, for example in mild male factor, unexplained infertility or when ovulation is induced and the tubes are open.
Where a structural problem is identified, minimally invasive surgery may help. Hysteroscopy can be used to remove polyps or septa and divide adhesions, while laparoscopy may be used for endometriosis, ovarian cysts, adhesions or fibroids when clinically appropriate. Surgery is recommended only when it is likely to benefit fertility.
IVF may be advised for blocked tubes, reduced ovarian reserve, endometriosis, male factor infertility, unexplained infertility that has not responded to simpler treatment, or after other treatments have not worked. Eggs are collected, fertilised in the laboratory and the resulting embryo is transferred to the uterus.
Your first appointment is a conversation as much as an examination. You will be able to discuss your concerns, share your reports, and understand which tests are needed and why. After the initial assessment, you will be given a clear explanation of the likely causes, the options available, and the expected timeline, so that you can make informed decisions at your own pace.
Please bring previous reports, prescriptions and details of any earlier treatment, and, if possible, attend together with your partner.
Dr. Sunita Arora is an obstetrician, gynaecologist and fertility specialist with more than 23 years of experience. She holds an MBBS from Lady Hardinge Medical College, New Delhi, and an MD in Obstetrics and Gynaecology from UCMS and GTB Hospital, and she is a Fellow of the Indian College of Obstetricians and Gynaecologists (FICOG) and a Fellow of the International College of Surgeons (FICS). She completed a fellowship in Reproductive Medicine at D.Y. Patil University, Mumbai, and received IVF training at RMA, Mount Sinai, New York.
Her areas of interest include infertility, IUI, IVF and endoscopic surgery.
Patients value a personalised, transparent approach in which each step of evaluation and treatment is explained in plain language.
She consults at Safdarjung Enclave and is also associated with Fortis La Femme, Greater Kailash II, which makes care accessible to women across South Delhi.
Dr Sunita Arora Fertility and Gynae Clinic
Fortis La Femme, South Delhi
Accessible to women across South Delhi, including Greater Kailash, Green Park, Hauz Khas and surrounding areas.
Find answers to common questions about female infertility causes, evaluation tests, and treatment options.